1-(chlorophenylmethyl)-4-fluorobenzene

  • Name:1-(chlorophenylmethyl)-4-fluorobenzene
  • CAS:365-21-9
  • Purity:99%
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Details

1-(chlorophenylmethyl)-4-fluorobenzene Good Manufacturer supply High Quality 365-21-9

  • Molecular Formula:C13H10ClF
  • Molecular Weight:220.674
  • Vapor Pressure:0.00279mmHg at 25°C 
  • Refractive Index:1.566 
  • Boiling Point:294.8 °C at 760mmHg 
  • Flash Point:139.1 °C 
  • PSA:0.00000 
  • Density:1.191 g/cm3 
  • LogP:4.15390 

1-(chlorophenylmethyl)-4-fluorobenzene(Cas 365-21-9) Usage

InChI:InChI=1/C13H10ClF/c14-13(10-4-2-1-3-5-10)11-6-8-12(15)9-7-11/h1-9,13H

365-21-9 Relevant articles

Synthesis and biological evaluation of 1‐(Diarylmethyl)‐1h‐1,2,4‐triazoles and 1‐(diarylmethyl)‐1h‐imidazoles as a novel class of anti‐mitotic agent for activity in breast cancer

Ana, Gloria,Kelly, Patrick M.,Malebari, Azizah M.,Noorani, Sara,Nathwani, Seema M.,Twamley, Brendan,Fayne, Darren,O’boyle, Niamh M.,Zisterer, Daniela M.,Pimentel, Elisangela Flavia,Endringer, Denise Coutinho,Meegan, Mary J.

, p. 1 - 59 (2021/03/16)

We report the synthesis and biochemical ...

Visible Light-Catalyzed Benzylic C-H Bond Chlorination by a Combination of Organic Dye (Acr+-Mes) and N-Chlorosuccinimide

Xiang, Ming,Zhou, Chao,Yang, Xiu-Long,Chen, Bin,Tung, Chen-Ho,Wu, Li-Zhu

, p. 9080 - 9087 (2020/08/14)

By combining "N-chlorosuccinimide (NCS)"...

Design, synthesis, and molecular docking study of new piperazine derivative as potential antimicrobial agents

Patil, Mahadev,Noonikara Poyil, Anurag,Joshi, Shrinivas D.,Patil, Shivaputra A.,Patil, Siddappa A.,Bugarin, Alejandro

, (2019/09/06)

Herein, we describe the successful desig...

Synthesis and Anticancer Activity of 1-(1H -Indol-3-yl)-2-(4-diarylmethylpiperazine-1-yl)ethane-1,2-dione Derivatives

Jiang, Jun-Rong,Xu, Feng,Wu, Han-Gui

, (2016/08/04)

Several new 1-(4-diarylmethylpiperazine-...

365-21-9 Process route

4-fluorobenzophenone
345-83-5

4-fluorobenzophenone

1-(chlorophenylmethyl)-4-fluorobenzene
365-21-9

1-(chlorophenylmethyl)-4-fluorobenzene

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: NaBH4 / propan-2-ol
2: HCl, Drierite / CH2Cl2
With hydrogenchloride; calcium sulfate; sodium tetrahydroborate; In dichloromethane; isopropyl alcohol;
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol
2: thionyl chloride / dichloromethane / 20 °C
With sodium tetrahydroborate; thionyl chloride; In methanol; dichloromethane;
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol
2: hydrogenchloride; tetrabutylammomium bromide / water / 40 - 45 °C
With hydrogenchloride; sodium tetrahydroborate; tetrabutylammomium bromide; In methanol; water;
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; methanol / 0 °C
2: thionyl chloride / dichloromethane / 12 h / 20 °C
With methanol; sodium tetrahydroborate; thionyl chloride; In dichloromethane;
1-(chlorophenylmethyl)-4-fluorobenzene
365-21-9

1-(chlorophenylmethyl)-4-fluorobenzene

Conditions
Conditions Yield
With hydrogenchloride; calcium chloride; Petroleum ether; benzene;

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