4-anilino-1-benzylpiperidine-4-carboxamide
- Name: 4-anilino-1-benzylpiperidine-4-carboxamide
- CAS: 1096-03-3
- Purity: 99%
Details
Quality products?make an important contribution to long-term revenue and profitability. Reliable Quality 4-anilino-1-benzylpiperidine-4-carboxamide 1096-03-3 Hot Sale with Chinese Manufacturer
1.What is the 4-anilino-1-benzylpiperidine-4-carboxamide ?
4-anilino-1-benzylpiperidine-4-carboxamide is used as modulators of muscarinic receptors for treatment of CNS disorders
-
-
968-86-5
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile
-
-
1096-03-3
1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
at 20 ℃;
for 18h;
|
94%
|
|
With
sulfuric acid;
for 48h;
Ambient temperature;
|
90%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid;
at 25 - 30 ℃;
for 20h;
With
sodium hydroxide;
In
water;
at 0 ℃;
for 1.25h;
|
88.6%
|
|
With
sulfuric acid;
|
87%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
potassium carbonate;
In
dimethyl sulfoxide;
at 20 ℃;
With
dihydrogen peroxide;
In
water; dimethyl sulfoxide;
|
85%
|
|
With
sulfuric acid; trifluoroacetic acid;
at 45 - 50 ℃;
for 16h;
Inert atmosphere;
|
82%
|
|
With
sulfuric acid; trifluoroacetic acid;
at 45 - 50 ℃;
for 16h;
Inert atmosphere;
|
82%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid;
In
water;
at 0 - 20 ℃;
for 17h;
With
sodium hydroxide;
In
water;
at 0 ℃;
pH=12;
|
78%
|
|
With
sulfuric acid;
at 20 ℃;
for 16h;
|
77%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid;
at 0 - 25 ℃;
With
ammonia; water;
at 0 ℃;
|
73%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid; water;
at 20 - 55 ℃;
for 2h;
With
sodium hydroxide;
In
water;
pH=8;
|
56%
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid;
at 20 ℃;
for 18h;
With
ammonium hydroxide;
at 0 ℃;
|
28.3%
|
|
With
sulfuric acid;
|
|
|
With
sulfuric acid;
for 20h;
|
|
|
With
sulfuric acid;
at 25 ℃;
|
|
|
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile;
With
sulfuric acid;
at 25 ℃;
With
ammonia; water;
at 0 ℃;
|
|
|
With
sulfuric acid;
|
|
|
With
sulfuric acid; water;
|
|
|
With
sulfuric acid;
at 20 ℃;
for 18h;
|
-
-
3612-20-2
1-phenylmethyl-4-piperidone
-
-
1096-03-3
1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: 58 percent / aq. AcOH / 48 h / 20 °C
2: 77 percent / H2
SO4
/ 16 h / 20 °C
With
sulfuric acid; acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1: AcOH / H2
O / 48 h / Ambient temperature
2: 90percent H2
SO4
/ 20 h
With
sulfuric acid; acetic acid;
In
water;
|
|
|
Multi-step reaction
with
2
steps
1: 90 percent / acetic acid; H2
O / 45 h / 45 °C / Irradiation
2: 90 percent / conc. H2
SO4
/ 48 h / Ambient temperature
With
sulfuric acid;
In
water; acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1: acetic acid / isopropyl alcohol / 4 h / Cooling with ice; Reflux
2: sulfuric acid; trifluoroacetic acid / 16 h / 45 - 50 °C / Inert atmosphere
With
sulfuric acid; acetic acid; trifluoroacetic acid;
In
isopropyl alcohol;
|
|
|
Multi-step reaction
with
2
steps
1: acetic acid / 2.5 h / 0 - 20 °C
2: sulfuric acid / 18 h / 20 °C
With
sulfuric acid; acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1.1: acetic acid / 1.17 h / 0 - 40 °C
1.2: 0 °C / pH 10
2.1: sulfuric acid / 0 - 25 °C
2.2: 0 °C
With
sulfuric acid;
In
acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1: acetic acid
2: sulfuric acid
With
sulfuric acid; acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1.1: acetic acid / 2.5 h / 20 °C
2.1: sulfuric acid / 18 h / 20 °C
2.2: 0 °C
With
sulfuric acid; acetic acid;
|
|
|
Multi-step reaction
with
2
steps
1: acetic acid / 2.5 h / 0 - 20 °C
2: sulfuric acid / 18 h / 20 °C
With
sulfuric acid; acetic acid;
|
2.What is the CAS number for 4-anilino-1-benzylpiperidine-4-carboxamide ?
The CAS number of 4-anilino-1-benzylpiperidine-4-carboxamide is 1096-03-3.
More information of 4-anilino-1-benzylpiperidine-4-carboxamide 1096-03-3 are:
|
CAS?Number |
1096-03-3 |
|
Density |
1.201g/cm3 |
|
Melting Point |
186.8-188.2 °C |
|
Boiling Point |
522.9°Cat760mmHg |
|
Flash Point |
270.1°C |
|
Vapor Pressure |
4.95E-11mmHg at 25°C |
|
Refractive Index |
1.641 |
|
HS CODE |
2933399090 |
|
PSA |
58.36000 |
|
LogP |
3.32980 |
|
Pka |
15.37±0.20(Predicted) |
3.What are another words for 4-anilino-1-benzylpiperidine-4-carboxamide ?
Synonyms?for?4-anilino-1-benzylpiperidine-4-carboxamide 1096-03-3:Isonipecotamide,4-anilino-1-benzyl- (7CI,8CI);1-Benzyl-4-(phenylamino)piperidine-4-carboxamide; 4-Anilino-1-benzyl-4-piperidinecarboxamide;NSC 73749
4.What is the molecular formula of 4-anilino-1-benzylpiperidine-4-carboxamide?
The chemical formula of ?4-anilino-1-benzylpiperidine-4-carboxamide is?C19H23 N3 O which containing 19 Carbon atoms,23 Hydrogen atoms,3 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??4-anilino-1-benzylpiperidine-4-carboxamide?is 309.411.
5.What is 4-anilino-1-benzylpiperidine-4-carboxamide (1096-03-3) used for?
4-anilino-1-benzylpiperidine-4-carboxamide is a white solid compound with a complex molecular structure. It is characterized by the presence of an anilino group attached to a benzyl-substituted piperidine ring, which is further connected to a carboxamide group. 4-anilino-1-benzylpiperidine-4-carboxamide is known for its potential applications in the pharmaceutical industry, particularly as a modulator of muscarinic receptors.
InChI:InChI=1/C19H23N3O/c20-18(23)19(21-17-9-5-2-6-10-17)11-13-22(14-12-19)15-16-7-3-1-4-8-16/h1-10,21H,11-15H2,(H2,20,23)
Relevant articles related to 4-anilino-1-benzylpiperidine-4-carboxamide:
|
Article |
Source |
|
Amide to Ester Conversion: A Practical Route to the Carfentanil Class of Analgetics |
Taber, Douglass F.,Rahimizadeh, Mohammad , p. 4037 - 4038 (1992) |
|
Design, synthesis and biological evaluation of 2-arylaminopyrimidine derivatives bearing 1,3,8-triazaspiro[4,5]decan-4-one or piperidine-3-carboxamide moiety as novel Type-I1/2 ALK inhibitors |
Gong, Ping,Guo, Ming,Liu, Sicong,Miao, Xiuqi,Xing, Lingyun,Yin, Shiliang,Zhai, Xin,Zhang, Dajun,Zhang, Hong , (2019/12/26) |
6.Buy 4-anilino-1-benzylpiperidine-4-carboxamide with the best price .
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