4-anilino-1-benzylpiperidine-4-carboxamide

  • Name: 4-anilino-1-benzylpiperidine-4-carboxamide
  • CAS: 1096-03-3
  • Purity: 99%
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1.What is the 4-anilino-1-benzylpiperidine-4-carboxamide ?

4-anilino-1-benzylpiperidine-4-carboxamide is used as modulators of muscarinic receptors for treatment of CNS disorders

1-benzyl-4-(phenylamino)piperidine-4-carbonitrile
968-86-5

1-benzyl-4-(phenylamino)piperidine-4-carbonitrile

1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide
1096-03-3

1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide

Conditions
Conditions Yield
With sulfuric acid; at 20 ℃; for 18h;
94%
With sulfuric acid; for 48h; Ambient temperature;
90%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; at 25 - 30 ℃; for 20h;
With sodium hydroxide; In water; at 0 ℃; for 1.25h;
88.6%
With sulfuric acid;
87%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With potassium carbonate; In dimethyl sulfoxide; at 20 ℃;
With dihydrogen peroxide; In water; dimethyl sulfoxide;
85%
With sulfuric acid; trifluoroacetic acid; at 45 - 50 ℃; for 16h; Inert atmosphere;
82%
With sulfuric acid; trifluoroacetic acid; at 45 - 50 ℃; for 16h; Inert atmosphere;
82%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; In water; at 0 - 20 ℃; for 17h;
With sodium hydroxide; In water; at 0 ℃; pH=12;
78%
With sulfuric acid; at 20 ℃; for 16h;
77%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; at 0 - 25 ℃;
With ammonia; water; at 0 ℃;
73%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; water; at 20 - 55 ℃; for 2h;
With sodium hydroxide; In water; pH=8;
56%
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; at 20 ℃; for 18h;
With ammonium hydroxide; at 0 ℃;
28.3%
With sulfuric acid;
With sulfuric acid; for 20h;
With sulfuric acid; at 25 ℃;
1-benzyl-4-(phenylamino)piperidine-4-carbonitrile; With sulfuric acid; at 25 ℃;
With ammonia; water; at 0 ℃;
With sulfuric acid;
With sulfuric acid; water;
With sulfuric acid; at 20 ℃; for 18h;
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide
1096-03-3

1-benzyl-4-phenylaminopiperidine-4-carboxylic acid amide

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 58 percent / aq. AcOH / 48 h / 20 °C
2: 77 percent / H2 SO4 / 16 h / 20 °C
With sulfuric acid; acetic acid;
Multi-step reaction with 2 steps
1: AcOH / H2 O / 48 h / Ambient temperature
2: 90percent H2 SO4 / 20 h
With sulfuric acid; acetic acid; In water;
Multi-step reaction with 2 steps
1: 90 percent / acetic acid; H2 O / 45 h / 45 °C / Irradiation
2: 90 percent / conc. H2 SO4 / 48 h / Ambient temperature
With sulfuric acid; In water; acetic acid;
Multi-step reaction with 2 steps
1: acetic acid / isopropyl alcohol / 4 h / Cooling with ice; Reflux
2: sulfuric acid; trifluoroacetic acid / 16 h / 45 - 50 °C / Inert atmosphere
With sulfuric acid; acetic acid; trifluoroacetic acid; In isopropyl alcohol;
Multi-step reaction with 2 steps
1: acetic acid / 2.5 h / 0 - 20 °C
2: sulfuric acid / 18 h / 20 °C
With sulfuric acid; acetic acid;
Multi-step reaction with 2 steps
1.1: acetic acid / 1.17 h / 0 - 40 °C
1.2: 0 °C / pH 10
2.1: sulfuric acid / 0 - 25 °C
2.2: 0 °C
With sulfuric acid; In acetic acid;
Multi-step reaction with 2 steps
1: acetic acid
2: sulfuric acid
With sulfuric acid; acetic acid;
Multi-step reaction with 2 steps
1.1: acetic acid / 2.5 h / 20 °C
2.1: sulfuric acid / 18 h / 20 °C
2.2: 0 °C
With sulfuric acid; acetic acid;
Multi-step reaction with 2 steps
1: acetic acid / 2.5 h / 0 - 20 °C
2: sulfuric acid / 18 h / 20 °C
With sulfuric acid; acetic acid;

2.What is the CAS number for 4-anilino-1-benzylpiperidine-4-carboxamide ?

The CAS number of 4-anilino-1-benzylpiperidine-4-carboxamide is 1096-03-3.

More information of 4-anilino-1-benzylpiperidine-4-carboxamide 1096-03-3 are:

CAS?Number

1096-03-3

Density

1.201g/cm3

Melting Point

186.8-188.2 °C

Boiling Point

522.9°Cat760mmHg

Flash Point

270.1°C

Vapor Pressure

4.95E-11mmHg at 25°C

Refractive Index

1.641

HS CODE

2933399090

PSA

58.36000

LogP

3.32980

Pka

15.37±0.20(Predicted)

3.What are another words for 4-anilino-1-benzylpiperidine-4-carboxamide ?

Synonyms?for?4-anilino-1-benzylpiperidine-4-carboxamide 1096-03-3:Isonipecotamide,4-anilino-1-benzyl- (7CI,8CI);1-Benzyl-4-(phenylamino)piperidine-4-carboxamide; 4-Anilino-1-benzyl-4-piperidinecarboxamide;NSC 73749

4.What is the molecular formula of 4-anilino-1-benzylpiperidine-4-carboxamide?

The chemical formula of ?4-anilino-1-benzylpiperidine-4-carboxamide is?C19H23 N3 O which containing 19 Carbon atoms,23 Hydrogen atoms,3 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??4-anilino-1-benzylpiperidine-4-carboxamide?is 309.411.

5.What is 4-anilino-1-benzylpiperidine-4-carboxamide (1096-03-3) used for?

4-anilino-1-benzylpiperidine-4-carboxamide is a white solid compound with a complex molecular structure. It is characterized by the presence of an anilino group attached to a benzyl-substituted piperidine ring, which is further connected to a carboxamide group. 4-anilino-1-benzylpiperidine-4-carboxamide is known for its potential applications in the pharmaceutical industry, particularly as a modulator of muscarinic receptors.

InChI:InChI=1/C19H23N3O/c20-18(23)19(21-17-9-5-2-6-10-17)11-13-22(14-12-19)15-16-7-3-1-4-8-16/h1-10,21H,11-15H2,(H2,20,23)

Relevant articles related to 4-anilino-1-benzylpiperidine-4-carboxamide:

Article

Source

Amide to Ester Conversion: A Practical Route to the Carfentanil Class of Analgetics

Taber, Douglass F.,Rahimizadeh, Mohammad

, p. 4037 - 4038 (1992)

Design, synthesis and biological evaluation of 2-arylaminopyrimidine derivatives bearing 1,3,8-triazaspiro[4,5]decan-4-one or piperidine-3-carboxamide moiety as novel Type-I1/2 ALK inhibitors

Gong, Ping,Guo, Ming,Liu, Sicong,Miao, Xiuqi,Xing, Lingyun,Yin, Shiliang,Zhai, Xin,Zhang, Dajun,Zhang, Hong

, (2019/12/26)

6.Buy 4-anilino-1-benzylpiperidine-4-carboxamide with the best price .

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